People with lower levels of insulin & insulin receptors in their brain often have Alzheimer’s disease. Researchers have learned that, as well as the pancreas, the brain also produces insulin.
They discovered that without insulin your brain cells will die. A drop in insulin production in your brain may contribute to the degeneration of your brain cells.
Studies since 2005 have continually documented that insulin has a much greater role in the brain than previously expected. Insulin is directly responsible for neuronal glucose-uptake, and the regulation of neurotransmitters like acetylcholine, which are crucial for memory and learning. Scientists have come to understand that cognition is impaired when insulin levels are reduced.
The clinical research has made it quite clear that the same pathological process that leads to insulin resistance and type 2 diabetes may also hold true for your brain. The take away from these studies make a strong point that the over-consumption of sugars and “grains” which are also detrimental to the the development of diabetes may also result in Type 3 Diabetes (brain diabetes). When the brain becomes overwhelmed by the consistently high levels of glucose, the insulin signaling will eventually become blunted or desensitized. This will lead to impairments in your thinking and memory abilities, eventually causing permanent brain damage.
Healthcare clinicians trained in functional medicine have the training and knowledge to investigate what is at the root of the pathological process that leads to Type 2 diabetes and the “new” diagnosis of Type 3 diabetes. The one size fits all approach of prescriptive medications for diabetes, although of some value, will not shut down the physiological cascade of the consequences of poor sugar/insulin control.
- Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer’s disease–is this type 3 diabetes? J Alzheimers Dis. 2005 Feb;7(1):63-80.
- de la Monte, Wands.Alzheimer’s Disease Is Type 3 Diabetes–Evidence Reviewed, J Diabetes Sci Technol. 2008 Nov; 2(6): 1101–1113.